HEMOPOIETIC EFFECT OF AQUEOUS EXTRACT OF THE LEAF SHEATH OF SORGHUM BICOLOR IN ALBINO RATS

Authors

  • O.O. OGWUMIKE Author

DOI:

https://doi.org/10.4314/

Keywords:

Sorghum Bicolor, Leaf Sheaths, Rats, Blood

Abstract

The effect of an aqueous extract of the leaf sheath of Sorghum bicolor on hemoglobin (Hb), red blood cell count 
(RBC), packed cell volume (PCV), mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV) and mean 
corpuscular hemoglobin concentration (MCHC) was investigated in 50 albino rats. The rats were in 5 groups of 10 
animals per group. The firs group is the control and the 4 other groups were the experimental. These latter groups 
were given oral treatments of the sorghum extract in concentrations of 200mg/kg, 400ng/kg, 800mg/kg and 
1,600mg/kg respectively for 16 days. Blood analysis was done at the end of 16 days. The extract of the leaf sheath 
of sorghum increased in a dose dependent manner Hb (P < 0.05), RBC (P < 0.05), PCV (P < 0.05) and MCH (P < 
0.001). It however caused a decrease in MCV (P < 0.05 and MCH (P < 0.05).. The result of this study thus supports 
the traditional use of sorghum bicolor as a remedy for anemia. 

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Published

2024-09-15

Issue

Vol. 5 No. 1&2 (2002): Combined Issue

Section

Original Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

HEMOPOIETIC EFFECT OF AQUEOUS EXTRACT OF THE LEAF SHEATH OF SORGHUM BICOLOR IN ALBINO RATS. (2024). African Journal of Biomedical Research, 5(1&amp;2), 69-71. https://doi.org/10.4314/