LIPOLYTIC EFFECT OF CALOTROPIS PROCERA IN THE SKIN OF WISTAR RATS

Authors

  • A.K. AKINLOYE Author
  • M.O. ABATAN Author
  • S.C. ONWUKA Author
  • O.O. ALAKA Author
  • B.O. OKE Author

DOI:

https://doi.org/10.4314/

Keywords:

Calotropis procera, lipolysis, skin, rat

Abstract

Histopathological studies of skin samples from Wistar rats treated once daily for four weeks with 20mg/gm body 
weight of the fresh leaf extract of Calotropis procera by the oral route showed significant degeneration of adipose 
tissue in the hypodermis and partial degeneration of the dermis at the site of merging with the hypodermis. No 
significant histological changes were, however, observed in the stratified squamous epithelium of the epidermis. Hair 
follicles and sebaceous glands were not affected. It was concluded from these observations that the subcutaneous 
layer was the one mainly affected by the treatment with the leaf extract

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Published

2024-09-15

Issue

Vol. 4 No. 3 (2001): September Issue

Section

Original Article

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

LIPOLYTIC EFFECT OF CALOTROPIS PROCERA IN THE SKIN OF WISTAR RATS. (2024). African Journal of Biomedical Research, 4(3), 143-145. https://doi.org/10.4314/

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