Anaesthetic Management Of Charcot-Marie-Tooth Disease For Left Foot Arthrodesis - A Case Report

Abstract

Charcot-Marie-Tooth disease (CMT) is one of the most common inherited polyneuropathic disorder occurring due to a genetic mutation, causing distal to proximal muscular weakness. Also known as hereditary motor and sensory neuropathy (HMSN), it may be autosomal dominant, autosomal recessive or X-linked. Anaesthetic management of patients with CMT disease differs from normal patients due to post-operative complications seen after use of muscle relaxants or inhalational agents causing serious complications including prolonged paralysis, respiratory issues or malignant hyperthermia. We report a successfully managed patient with CMT by careful titration of propofol based total intravenous anaesthesia (TIVA) coupled with selective use of regional blocks as a reliable and safe strategy.  This tailored anaesthetic approach ensured safety and avoided complications. With vigilant intraoperative management and appropriate anaesthetic choices, surgery can be performed safely in patients with CMT.