The Multifaceted Burden of Vitiligo: Global Epidemiology, Complex Etiology, Signalling, and Emerging Therapeutic Interventions

Authors

  • Heena Javed Aga Author
  • Altaf Ahmad Shah Author
  • Salman Akhtar Author

DOI:

https://doi.org/10.53555/AJBR.v26i3.7721

Keywords:

Vitiligo, Personalized medicine, melanocytes, autoimmune disorder, CD8+ cells, IFN-γ, depigmentation

Abstract

Vitiligo, a complicated skin condition characterized by depigmented patches, has far-reaching ramifications for both affected people and the medical community. This article gives a succinct assessment of the condition's importance, prevalence, and devastating impact on the lives of individuals affected. Vitiligo prevalence varies among populations and age ranges, affecting both genders and people of various races. Beyond its physical manifestations, vitiligo has a significant psychosocial impact, frequently impairing self-esteem, body image, and general quality of life. This article serves as a precursor to a more in-depth examination of vitiligo's multidimensional character, including its underlying causes, treatment choices, etiology, and the revolutionary potential of bioinformatics for personalized precision. By projecting light on the complexity of vitiligo and its far-reaching impacts, this article sets the ground for a complete assessment that aims to increase our understanding and improve the care of people suffering from this perplexing skin condition.

Author Biographies

  • Heena Javed Aga

    Department of Biosciences, Integral University, Lucknow, India.

  • Altaf Ahmad Shah

    Department of Bioengineering, Faculty of Engineering, Integral University, Lucknow, India.

  • Salman Akhtar

    Department of Bioengineering, Faculty of Engineering, Integral University, Lucknow, India.

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Published

2023-12-24

Issue

Section

Review Article

How to Cite

The Multifaceted Burden of Vitiligo: Global Epidemiology, Complex Etiology, Signalling, and Emerging Therapeutic Interventions. (2023). African Journal of Biomedical Research, 26(3), 527-546. https://doi.org/10.53555/AJBR.v26i3.7721