Role Of Vitamin D3 In Women with Unexplained Recurrent Miscarriage

Abstract

Miscarriage known as the  loss of pregnancy before the twenty week and it is a distressing event that many women experience even with un-explanation. This study aim to assess the role of Vitamin D3 in women with unexplained recurrent-miscarriages and its effects on fertility and pregnancy-outcomes. A total of 124 participant women in aged 19 to 44 years with a history of two or more miscarriages were involved in this study. Participants were classified into two groups based on their Vitamin D3 levels: normal(N=35) and deficient (N=89). Blood samples were collected and analyzed for Vitamin D3 levels. Results indicate that women with Vitamin D3 deficiency had significantly lower levels of Vitamin D3 (17.76 ± 0.81 ng/ml) compared to those with normal levels (36.23 ± 0.93 ng/ml), with a p-value of <0.0001. Additionally, no significant difference in age was found between the two groups, but a significant difference in BMI was observed, with the deficient group showing a higher BMI (26.91 ± 0.40) compared to the normal group (24.71 ± 0.74) with a p-value of 0.0066. The study concludes that Vitamin D3 plays a crucial role in women with recurrent miscarriage also Vitamin D3 levels may help reduce the risk of recurrent-miscarriage and improve pregnancy outcomes.