Perception, Acceptance and Uptake of Human Papillomavirus Vaccine among Female Adolescents in Selected Secondary Schools in Ibadan, Nigeria

Abstract

Infection with Human papillomavirus (HPV) contributes to malignant changes in the cervix leading to cancer mortality among 
women. HPV vaccine is now available for its prevention, yet the level of uptake is low. The study aimed at determining 
Perception, Acceptance and Uptake of Human papillomavirus Vaccine among female adolescents in selected secondary schools 
in Ibadan, Nigeria. This cross-sectional study was conducted among 296 female adolescent senior secondary school students in 
Ibadan, Nigeria. Respondents were selected using purposive sampling method and data were collected using self-administered 
questionnaire. The data were analysed using the Statistical Package for Social Sciences version 20.0. Variables were presented 
as frequency tables and hypotheses were tested using chi-square and Fisher’s exact test at P≤ 0.05. Most 142(48.0%) of the 
respondents were between ages 15-17. The respondents’ perception and knowledge about HPV vaccine, HPV infection and 
cervical cancer was generally poor. Furthermore, only 12(4.1%) of the respondents have received the HPV vaccine before the 
study. There is a significant association between adolescent’s perception and uptake of HPV vaccine p=0.000 as well as 
Perception and readiness for the use of HPV vaccine (p=0.007). Parental approval and readiness for HPV vaccine uptake were 
found to be significantly associated (p =0.000). Since knowledge about Human Papilloma Virus Vaccination is quite low, there 
is need to increase awareness about the Vaccination among female adolescents and their mothers. Also, peer educators in schools 
can be trained to improve awareness in schools so as to reduce the incidence of cervical cancer.